Activation of neuronal CB1 receptors brings about inhibition of adenylyl cyclase and decreased neurotransmitter release as a result of blockade of voltage-operated calcium channels.[46,sixty five,125] The activation of such signaling pathways by CB1 receptors and the high amounts of these receptors on presynaptic terminals indicates that endocannabinoid stimulation of CB1 https://insuranceclaimsassistance09627.answerblogs.com/33025741/the-2-minute-rule-for-cannabis-strains